RBM5-AS1

Across TCGA pan-cancer cohorts, RBM5-AS1 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of RBM5-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where RBM5-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types RBM5-AS1 is over-expressed in tumor, although a few such as THCA and BRCA show the opposite, repressed pattern.

THCA, BLCA, and BRCA are the cancer types where RBM5-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RBM5-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	All	−0.238	.001	6	view →
BLCA	Female	All	+0.221	.014	4	view →
BRCA	Female	All	−0.169	.011	4	view →
LIHC	Female	All	+0.138	<.001	4	view →
LUSC	All	All	−0.169	.007	2	view →
CHOL	All	All	+0.295	.021	1	view →
STAD	All	II,III,IV	+0.222	.046	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

RBM5-AS1–THCA

Open the THCA breakdown →