RBM47

Across TCGA patient cohorts, RBM47 mutation is significantly associated with the total protein of many other genes, with 52 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBM47-associated genes across cancer lineages are GAPDH, Notch1, and PDCD4. Each is linked with RBM47 in more than 2 cancer types. Because this analysis shows association rather than direction, both RBM47-to-partner and partner-to-RBM47 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAPDH grouped by RBM47-low versus RBM47-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM47→partner) and Y-score (partner→RBM47) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	GAPDH →	+0.463	+2.415	.020	.003	3	3
STAD	Notch1 →	+0.295	+3.169	<.001	.018	3	2
STAD	PDCD4 →	-0.649	-3.321	.001	.010	3	2
UCEC	eIF4E →	+0.138	+2.013	.040	.016	3	2
UCEC	JNK_pT183_Y185 →	-0.157	-1.510	.003	.008	3	2
UCEC	PCNA →	+0.235	+1.777	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 52 associations by consensus.

GAPDH by RBM47 expression — SKCM

Explore this box plot interactively →