RBM44

Across TCGA patient cohorts, RBM44 mutation is significantly associated with the RNA expression of many other genes, with 3,254 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBM44-associated genes across cancer lineages are OR4A5, FAM177A1, and VPS26B. Each is linked with RBM44 in more than 2 cancer types. Because this analysis shows association rather than direction, both RBM44-to-partner and partner-to-RBM44 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4A5 grouped by RBM44-low versus RBM44-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM44→partner) and Y-score (partner→RBM44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	OR4A5 →	+0.055	+7.725	<.001	<.001	3	3
UCEC	FAM177A1 →	+0.330	+2.202	<.001	.001	3	2
UCEC	VPS26B →	+0.309	+1.557	.002	.001	3	2
UCEC	CENPU →	+0.604	+2.364	<.001	<.001	3	2
COAD	SLC25A4 →	+0.535	+3.223	.002	.009	3	2
UCEC	HAUS1 →	+0.400	+2.021	.003	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,254 associations by consensus.

OR4A5 by RBM44 expression — BRCA

Explore this box plot interactively →