RBM44

Across TCGA patient cohorts, RBM44 mutation is significantly associated with the total protein of many other genes, with 50 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBM44-associated genes across cancer lineages are 4E-BP1, Ku80, and ASNS. Each is linked with RBM44 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBM44-to-partner and partner-to-RBM44 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 4E-BP1 grouped by RBM44-low versus RBM44-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM44→partner) and Y-score (partner→RBM44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	4E-BP1 →	+0.391	+3.247	<.001	<.001	3	2
UCEC	Ku80 →	+0.219	+1.598	.003	.003	3	2
UCEC	ASNS →	+0.410	+2.321	<.001	<.001	3	2
UCEC	Caspase-7-cleavedD198 →	+0.464	+2.522	.012	<.001	3	2
UCEC	Caveolin-1 →	-0.486	-1.584	.033	.017	3	2
UCEC	4E-BP1_pT70 →	+0.076	+1.353	.035	.015	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 50 associations by consensus.

4E-BP1 by RBM44 expression — UCEC

Explore this box plot interactively →