RBM44

Across TCGA cell cohorts, RBM44 mutation is significantly associated with the RNA expression of many other genes, with 106 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RBM44-associated genes across cancer lineages are METTL4, BET1, and PMP22. Each is linked with RBM44 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBM44-to-partner and partner-to-RBM44 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, METTL4 grouped by RBM44-low versus RBM44-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM44→partner) and Y-score (partner→RBM44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	METTL4 →	+0.681	+3.364	<.001	.002	3	1
LARGE_INTESTINE	BET1 →	+0.483	+3.451	.004	.002	3	1
LARGE_INTESTINE	PMP22 →	+1.544	+3.364	.001	.002	3	1
LARGE_INTESTINE	GPR63 →	+0.907	+3.364	<.001	.002	3	1
LARGE_INTESTINE	SLC17A5 →	+0.824	+3.169	<.001	.006	3	1
LARGE_INTESTINE	MAGEB4 →	+0.009	+3.000	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 106 associations by consensus.

METTL4 by RBM44 expression — LARGE_INTESTINE

Explore this box plot interactively →