RBM26

Across TCGA patient cohorts, RBM26 mutation is significantly associated with the total protein of many other genes, with 52 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBM26-associated genes across cancer lineages are TFRC, Ku80, and PCNA. Each is linked with RBM26 in more than 3 cancer types. Because this analysis shows association rather than direction, both RBM26-to-partner and partner-to-RBM26 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TFRC grouped by RBM26-low versus RBM26-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM26→partner) and Y-score (partner→RBM26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TFRC →	+0.515	+3.807	.001	<.001	3	4
UCEC	Ku80 →	+0.177	+1.428	.016	.006	3	3
UCEC	PCNA →	+0.269	+1.893	<.001	<.001	3	3
UCEC	GAPDH →	+0.442	+1.643	.007	.003	3	2
UCEC	GATA6 →	-0.107	-1.130	.027	.041	3	2
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.316	+1.201	.045	.028	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 52 associations by consensus.

TFRC by RBM26 expression — UCEC

Explore this box plot interactively →