RBM23

Across TCGA cell cohorts, RBM23 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,563 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RBM23-associated GO terms across cancer lineages are Regulation of transcription initiation by RNA polymerase II, Regulation of mRNA splicing, via spliceosome, and Nuclear transport. Each is linked with RBM23 in more than 14 cancer types. Because this analysis shows association rather than direction, both RBM23-to-partner and partner-to-RBM23 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of transcription initiation by RNA polymerase II grouped by RBM23-low versus RBM23-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM23→partner) and Y-score (partner→RBM23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of transcription initiation by RNA polymerase II →	+0.069	+0.744	<.001	.002	3	15
KIDNEY	Regulation of mRNA splicing, via spliceosome →	+0.073	+0.954	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Nuclear transport →	+0.064	+1.038	.002	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Nucleocytoplasmic transport →	+0.064	+1.038	.002	<.001	3	15
BREAST	Regulation of mitotic cytokinesis →	+0.164	+1.161	<.001	<.001	3	15
KIDNEY	Positive regulation of cytokinesis →	+0.134	+0.986	<.001	.002	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,563 associations by consensus.

Regulation of transcription initiation by RNA polymerase II by RBM23 expression — SOFT_TISSUE

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