RBM15B

Across TCGA patient cohorts, RBM15B mutation is significantly associated with the RNA expression of many other genes, with 7,799 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBM15B-associated genes across cancer lineages are RNU6-13P, TOMM22P5, and HMGB3P15. Each is linked with RBM15B in more than 2 cancer types. Because this analysis shows association rather than direction, both RBM15B-to-partner and partner-to-RBM15B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-13P grouped by RBM15B-low versus RBM15B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM15B→partner) and Y-score (partner→RBM15B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-13P →	+0.180	+1.600	.001	.004	3	3
UCEC	TOMM22P5 →	+0.211	+1.630	<.001	<.001	3	3
SKCM	HMGB3P15 →	+0.062	+5.797	<.001	.001	3	2
UCEC	GCAT →	+0.617	+2.813	<.001	<.001	3	2
UCEC	CENPM →	+0.539	+2.673	<.001	<.001	3	2
UCEC	MCAT →	+0.368	+3.212	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,799 associations by consensus.

RNU6-13P by RBM15B expression — UCEC

Explore this box plot interactively →