RBM15-AS1

Across TCGA pan-cancer cohorts, RBM15-AS1 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated RBM15-AS1 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher RBM15-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RBM15-AS1 expression acts as an unfavorable survival marker, although some lineages such as PAAD and OV show a favorable association.

KIRP, KIRC, and UVM are the cancer types where RBM15-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Tertile	All	0.462	0.782	<.001	136	view →
KIRC	DFS	Quartile	All	0.813	0.947	<.001	121	view →
UVM	DFS	Quartile	All	0.328	0.761	<.001	99	view →
KICH	DFS	Median	II,III,IV	0.554	0.922	.002	47	view →
PAAD	DFS	Tertile	All	0.400	0.168	<.001	44	view →
LGG	DFS	Median	All	0.661	0.808	<.001	36	view →
LIHC	OS	Median	All	0.610	0.789	<.001	36	view →
COAD	OS	Tertile	III,IV	0.642	0.900	.003	33	view →
ACC	OS	Quartile	All	0.817	1.000	.007	25	view →
SARC	OS	Median	All	0.765	0.903	<.001	23	view →
OV	DFS	Median	IV	0.539	0.368	.023	16	view →
LUSC	OS	Median	II,III,IV	0.810	0.517	.005	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

RBM15-AS1–KIRP (OS)

Open the KIRP breakdown →