RBM15-AS1

Across TCGA pan-cancer cohorts, RBM15-AS1 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of RBM15-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where RBM15-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RBM15-AS1 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

LIHC, BLCA, and LUAD are the cancer types where RBM15-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RBM15-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	Male	All	+0.503	<.001	9	view →
BLCA	All	All	+0.252	<.001	8	view →
LUAD	All	II,III,IV	+0.221	<.001	8	view →
KIRC	Female	II,III,IV	+0.216	.001	8	view →
KICH	All	All	−0.367	<.001	6	view →
UCEC	All	All	+0.275	<.001	6	view →
STAD	All	II,III,IV	+0.249	<.001	6	view →
BRCA	All	II,III,IV	+0.171	<.001	6	view →
THCA	All	All	−0.118	<.001	6	view →
HNSC	All	II,III,IV	+0.098	.004	6	view →
COAD	All	All	+0.178	.003	4	view →
READ	Female	All	+0.367	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

RBM15-AS1–LIHC

Open the LIHC breakdown →