RBM14-RBM4

Across TCGA pan-cancer cohorts, RBM14-RBM4 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated RBM14-RBM4 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher RBM14-RBM4 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RBM14-RBM4 expression acts as an unfavorable survival marker, although some lineages such as UCS and THYM show a favorable association.

KICH, ACC, and KIRC are the cancer types where RBM14-RBM4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	III,IV	0.199	0.931	<.001	89	view →
ACC	DFS	Tertile	All	0.222	0.644	<.001	88	view →
KIRC	DFS	Median	IV	0.175	0.487	<.001	41	view →
COAD	OS	Tertile	All	0.515	0.714	.005	38	view →
UCS	DFS	Median	IV	0.952	0.367	.001	38	view →
THYM	DFS	Tertile	II,III,IV	0.914	0.537	.002	29	view →
LGG	DFS	Median	All	0.788	0.874	.001	28	view →
KIRP	DFS	Tertile	All	0.584	0.834	.003	25	view →
GBM	DFS	Quartile	All	0.526	0.213	.001	24	view →
PRAD	DFS	Median	All	0.843	0.925	.002	18	view →
SCLC	DFS	Tertile	II,III,IV	0.976	0.356	.006	16	view →
UCEC	DFS	Tertile	All	0.797	0.887	.009	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

RBM14-RBM4–KICH (DFS)

Open the KICH breakdown →