Across TCGA patient cohorts, RBM12B mutation is significantly associated with the RNA expression of many other genes, with 4,314 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBM12B-associated genes across cancer lineages are RPARP-AS1, TAF9, and PINCR. Each is linked with RBM12B in more than 2 cancer types. Because this analysis shows association rather than direction, both RBM12B-to-partner and partner-to-RBM12B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM12B→partner) and Y-score (partner→RBM12B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	RPARP-AS1 →	+0.611	+3.219	<.001	.009	3	3
UCEC	TAF9 →	+0.575	+2.758	<.001	<.001	3	3
UCEC	PINCR →	+0.241	+1.600	<.001	<.001	3	3
STAD	BCAS2 →	+0.492	+3.355	<.001	.005	3	3
STAD	NARS1 →	+0.535	+3.338	.005	.005	3	3
STAD	ZCCHC7 →	+0.642	+3.355	<.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,314 associations by consensus.

Exploration

RBM12B survival (RNA) · tumor vs normal (RNA) · all RBM12B data types