Across TCGA patient cohorts, RBM11 mutation is significantly associated with the RNA expression of many other genes, with 993 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBM11-associated genes across cancer lineages are PPP4C, SEC13, and MED8. Each is linked with RBM11 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBM11-to-partner and partner-to-RBM11 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM11→partner) and Y-score (partner→RBM11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PPP4C →	+0.369	+3.130	.005	<.001	3	2
UCEC	SEC13 →	+0.507	+3.839	<.001	<.001	3	2
UCEC	MED8 →	+0.307	+2.724	.008	.003	3	2
UCEC	HK3 →	+0.973	+2.436	<.001	.002	3	2
UCEC	STX5 →	+0.362	+3.475	.005	.002	3	2
UCEC	PPIH →	+0.430	+3.338	.002	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 993 associations by consensus.

Exploration

RBM11 survival (RNA) · tumor vs normal (RNA) · all RBM11 data types