RBM10

Across TCGA patient cohorts, RBM10 mutation is significantly associated with the RNA expression of many other genes, with 3,655 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBM10-associated genes across cancer lineages are BBS5, RNPEP, and NEIL3. Each is linked with RBM10 in more than 2 cancer types. Because this analysis shows association rather than direction, both RBM10-to-partner and partner-to-RBM10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BBS5 grouped by RBM10-low versus RBM10-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM10→partner) and Y-score (partner→RBM10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	BBS5 →	+0.358	+3.212	.008	.009	3	3
BLCA	RNPEP →	+0.529	+3.516	<.001	.002	3	3
UCEC	NEIL3 →	+0.443	+2.153	.001	<.001	3	3
LUAD	CUTC →	+0.440	+2.807	<.001	<.001	3	3
UCEC	KNSTRN →	+0.350	+1.942	.009	.002	3	3
LUAD	RNA5SP247 →	+0.382	+1.885	.004	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,655 associations by consensus.

BBS5 by RBM10 expression — BLCA

Explore this box plot interactively →