RBM10

Across TCGA pan-cancer cohorts, RBM10 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of RBM10’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where RBM10 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RBM10 is over-expressed in tumor.

LIHC, COAD, and STAD are the cancer types where RBM10 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RBM10 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	Female	II,III,IV	+1.073	<.001	9	view →
COAD	All	III,IV	+0.509	<.001	9	view →
STAD	Male	II,III,IV	+0.952	<.001	8	view →
HNSC	Male	All	+0.712	<.001	8	view →
BLCA	All	All	+0.687	<.001	8	view →
LUSC	Male	II,III,IV	+0.580	<.001	7	view →
BRCA	All	All	+0.224	.006	6	view →
CHOL	Male	All	+1.770	<.001	5	view →
KIRC	Female	All	+0.355	.001	5	view →
READ	All	III,IV	+0.694	.001	4	view →
KIRP	All	II,III,IV	+0.443	.005	4	view →
ESCA	All	All	+0.716	.008	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

RBM10–LIHC

Open the LIHC breakdown →