RBM10

Across TCGA cell cohorts, RBM10 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,554 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RBM10-associated GO terms across cancer lineages are DNA strand elongation involved in DNA replication, Regulation of chromatin organization, and DNA-templated transcription initiation. Each is linked with RBM10 in more than 18 cancer types. Because this analysis shows association rather than direction, both RBM10-to-partner and partner-to-RBM10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA strand elongation involved in DNA replication grouped by RBM10-low versus RBM10-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM10→partner) and Y-score (partner→RBM10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	DNA strand elongation involved in DNA replication →	+0.217	+0.701	<.001	<.001	3	19
BREAST	Regulation of chromatin organization →	+0.096	+0.825	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	DNA-templated transcription initiation →	+0.105	+0.917	<.001	<.001	3	18
PANCREAS	Positive regulation of nuclear cell cycle DNA replication →	+0.160	+0.471	<.001	.002	3	17
BONE	mRNA alternative polyadenylation →	+0.104	+0.952	<.001	<.001	3	17
SOFT_TISSUE	Constitutive heterochromatin formation →	+0.117	+0.856	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,554 associations by consensus.

DNA strand elongation involved in DNA replication by RBM10 expression — SOFT_TISSUE

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