RBM10

Across TCGA cell cohorts, RBM10 mutation is significantly associated with the RNA expression of many other genes, with 296 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RBM10-associated genes across cancer lineages are OPN1MW3, ASB17, and C12orf40. Each is linked with RBM10 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBM10-to-partner and partner-to-RBM10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OPN1MW3 grouped by RBM10-low versus RBM10-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM10→partner) and Y-score (partner→RBM10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	OPN1MW3 →	+0.010	+4.614	<.001	.004	3	1
OVARY	ASB17 →	+0.014	+4.222	<.001	.006	3	1
OVARY	C12orf40 →	+0.010	+4.444	<.001	.001	3	1
OVARY	PAPOLB →	+0.011	+3.791	.001	.007	3	1
LARGE_INTESTINE	DYRK4 →	+0.807	+3.064	.003	.009	3	1
LARGE_INTESTINE	CCDC113 →	+0.694	+3.237	.008	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 296 associations by consensus.

OPN1MW3 by RBM10 expression — PANCREAS

Explore this box plot interactively →