RBL2

Across TCGA patient cohorts, RBL2 protein abundance is significantly associated with the RNA expression of many other genes, with 9,487 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible RBL2-associated genes across cancer lineages are E2F3, CENPO, and BCL2L12. Each is linked with RBL2 in more than 4 cancer types. Because this analysis shows association rather than direction, both RBL2-to-partner and partner-to-RBL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RBL2 versus E2F3 in BRCA, with a Pearson correlation of -0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBL2→partner) and Y-score (partner→RBL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	E2F3 →	-0.940	-0.273	<.001	<.001	3	5
BRCA	CENPO →	-0.658	-0.275	<.001	<.001	3	5
BRCA	BCL2L12 →	-0.711	-0.309	<.001	<.001	3	4
UCEC	OIP5 →	-0.730	-0.159	.001	.004	3	4
LUAD	NCAPG →	-0.992	-0.152	<.001	<.001	3	4
LUAD	ANLN →	-1.200	-0.167	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,487 associations by consensus.

RBL2 vs E2F3 — BRCA

Explore this scatter interactively →