RBL2

Across TCGA cell cohorts, RBL2 mutation is significantly associated with the RNA expression of many other genes, with 74 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RBL2-associated genes across cancer lineages are GSTT2, OR1L3, and IL17F. Each is linked with RBL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBL2-to-partner and partner-to-RBL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GSTT2 grouped by RBL2-low versus RBL2-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBL2→partner) and Y-score (partner→RBL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	GSTT2 →	+0.284	+4.191	<.001	.007	3	2
OVARY	OR1L3 →	+0.029	+2.859	<.001	.008	3	2
SOFT_TISSUE	IL17F →	+0.054	+4.930	<.001	.008	3	1
SOFT_TISSUE	FTMT →	+0.086	+5.977	<.001	.001	3	1
SOFT_TISSUE	CT45A7 →	+0.035	+4.930	<.001	.008	3	1
PANCREAS	KRTAP10-12 →	+0.026	+5.614	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 74 associations by consensus.

GSTT2 by RBL2 expression — BLOOD_Lymphoma

Explore this box plot interactively →