RBIS

Across TCGA patient cohorts, RBIS protein abundance is significantly associated with the RNA expression of many other genes, with 3,939 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible RBIS-associated genes across cancer lineages are CCT8, MTERF3, and DCAF13. Each is linked with RBIS in more than 3 cancer types. Because this analysis shows association rather than direction, both RBIS-to-partner and partner-to-RBIS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RBIS versus CCT8 in UCEC, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBIS→partner) and Y-score (partner→RBIS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CCT8 →	+0.575	+0.357	.005	.001	3	3
UCEC	MTERF3 →	+0.676	+0.292	.006	.003	3	3
UCEC	DCAF13 →	+0.554	+0.217	.002	.007	3	3
UCEC	MRPL13 →	+0.686	+0.288	.003	.004	3	3
COAD	SLC52A2 →	+0.821	+0.371	.002	.001	3	3
UCEC	SNHG6 →	+0.710	+0.232	.005	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,939 associations by consensus.

RBIS vs CCT8 — UCEC

Explore this scatter interactively →