RBIS

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RBIS mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. CESC shows the largest number of these associations.

The most reproducible RBIS-associated genes across cancer lineages are CD8+ Tcm. Each is linked with RBIS in more than 1 cancer types. Because this analysis shows association rather than direction, both RBIS-to-partner and partner-to-RBIS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ Tcm grouped by RBIS-low versus RBIS-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBIS→partner) and Y-score (partner→RBIS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCCD8+ Tcm →+0.084+3.918.011.03631
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

CD8+ Tcm by RBIS expression — CESC

Box plot of CD8+ Tcm in RBIS-low vs RBIS-high samples in CESC.

Explore this box plot interactively →

Exploration