RBCK1

Across TCGA patient cohorts, RBCK1 mutation is significantly associated with the RNA expression of many other genes, with 1,141 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBCK1-associated genes across cancer lineages are RNU6-550P, RNU1-57P, and LINC01075. Each is linked with RBCK1 in more than 2 cancer types. Because this analysis shows association rather than direction, both RBCK1-to-partner and partner-to-RBCK1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-550P grouped by RBCK1-low versus RBCK1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBCK1→partner) and Y-score (partner→RBCK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU6-550P →	+0.815	+5.038	<.001	.009	3	3
UCEC	RNU1-57P →	+0.219	+4.354	<.001	<.001	3	3
SKCM	LINC01075 →	+0.135	+5.292	<.001	.006	3	2
BLCA	EIF4EBP2P3 →	+0.132	+6.147	<.001	.002	3	2
BLCA	RN7SKP182 →	+0.307	+5.411	.004	.005	3	2
BLCA	VN1R66P →	+0.051	+6.289	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,141 associations by consensus.

RNU6-550P by RBCK1 expression — BLCA

Explore this box plot interactively →