RBCK1

Across TCGA cell cohorts, RBCK1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,298 significant associations in total. CNS shows the largest number of these associations.

The most reproducible RBCK1-associated GO terms across cancer lineages are Positive regulation of protein localization to endoplasmic reticulum, Regulation of protein localization to endoplasmic reticulum, and Regulation of plasma cell differentiation. Each is linked with RBCK1 in more than 17 cancer types. Because this analysis shows association rather than direction, both RBCK1-to-partner and partner-to-RBCK1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein localization to endoplasmic reticulum grouped by RBCK1-low versus RBCK1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RBCK1→partner) and Y-score (partner→RBCK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Positive regulation of protein localization to endoplasmic reticulum →	+0.107	+0.808	<.001	.005	3	18
UPPER_AERODIGESTIVE_TRACT	Regulation of protein localization to endoplasmic reticulum →	+0.125	+1.083	.001	.008	3	15
URINARY_TRACT	Regulation of plasma cell differentiation →	+0.136	+1.070	<.001	.002	3	14
LUNG_NSCLC_LUSC	Cilium or flagellum-dependent cell motility →	-0.079	-0.947	.001	.003	3	13
URINARY_TRACT	Positive regulation of plasma cell differentiation →	+0.156	+1.597	<.001	<.001	3	13
SOFT_TISSUE	Flagellated sperm motility →	-0.094	-1.309	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,298 associations by consensus.

Positive regulation of protein localization to endoplasmic reticulum by RBCK1 expression — BREAST

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