RBBP9

Across TCGA patient cohorts, RBBP9 mutation is significantly associated with the RNA expression of many other genes, with 174 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBBP9-associated genes across cancer lineages are SEPTIN7P4, RNA5SP397, and RNA5SP318. Each is linked with RBBP9 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBBP9-to-partner and partner-to-RBBP9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SEPTIN7P4 grouped by RBBP9-low versus RBBP9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBBP9→partner) and Y-score (partner→RBBP9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SEPTIN7P4 →	+0.110	+4.049	<.001	.008	3	2
LUSC	RNA5SP397 →	+0.296	+7.924	<.001	.008	3	1
LUSC	RNA5SP318 →	+0.937	+7.924	<.001	.008	3	1
UCEC	NPTN-IT1 →	+0.449	+3.257	.002	.008	3	1
UCEC	MIR3198-1 →	+1.020	+3.831	<.001	<.001	3	1
UCEC	MIR3659 →	+0.376	+4.231	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 174 associations by consensus.

SEPTIN7P4 by RBBP9 expression — UCEC

Explore this box plot interactively →