RBBP8NL

Across TCGA pan-cancer cohorts, RBBP8NL mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated RBBP8NL data layer compared with 24 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher RBBP8NL mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated RBBP8NL expression acts as an unfavorable survival marker, although some lineages such as UCEC and LSCC show a favorable association.

UCEC, LUAD, and LSCC are the cancer types where RBBP8NL mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Quartile	II,III,IV	1.000	0.458	.015	12	view →
LUAD	DFS	Quartile	III,IV	0.298	0.833	.016	6	view →
LSCC	DFS	Quartile	II,III,IV	0.929	0.534	.015	4	view →
HNSC	OS	Median	II,III,IV	0.788	0.921	.020	1	view →
PDAC	OS	Median	All	0.676	1.000	.031	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

RBBP8NL–UCEC (DFS)

Open the UCEC breakdown →