RBBP8NL

Across TCGA patient cohorts, RBBP8NL mutation is significantly associated with the total protein of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBBP8NL-associated genes across cancer lineages are p21, AR, and EGFR_pY1068. Each is linked with RBBP8NL in more than 1 cancer types. Because this analysis shows association rather than direction, both RBBP8NL-to-partner and partner-to-RBBP8NL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, p21 grouped by RBBP8NL-low versus RBBP8NL-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBBP8NL→partner) and Y-score (partner→RBBP8NL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	p21 →	-0.617	-3.000	.005	.035	3	1
SKCM	AR →	-0.182	-3.169	.023	.018	3	1
UCEC	EGFR_pY1068 →	-0.321	-3.000	.026	.037	3	1
UCEC	STAT3_pY705 →	-0.369	-3.000	.015	.037	3	1
UCEC	Caspase-7-cleavedD198 →	+1.033	+2.827	.002	.035	3	1
SKCM	HER2 →	+0.414	+2.820	.004	.035	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

p21 by RBBP8NL expression — SKCM

Explore this box plot interactively →