RBBP8NL

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, RBBP8NL mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. CNS shows the largest number of these associations.

The most reproducible RBBP8NL-associated genes across cancer lineages are KRT26, OR1D2, and HELT. Each is linked with RBBP8NL in more than 1 cancer types. Because this analysis shows association rather than direction, both RBBP8NL-to-partner and partner-to-RBBP8NL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRT26 grouped by RBBP8NL-low versus RBBP8NL-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBBP8NL→partner) and Y-score (partner→RBBP8NL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVARYKRT26 →+0.011+5.405<.001<.00131
LARGE_INTESTINEOR1D2 →+0.014+4.437<.001.00431
CNSHELT →+0.037+5.321<.001.00531
SKINSLC10A2 →+0.004+4.437<.001.00431
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

KRT26 by RBBP8NL expression — OVARY

Box plot of KRT26 in RBBP8NL-low vs RBBP8NL-high samples in OVARY.

Explore this box plot interactively →

Exploration