RBBP8

Across TCGA cell cohorts, RBBP8 mutation is significantly associated with the RNA expression of many other genes, with 42 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RBBP8-associated genes across cancer lineages are OOSP2, OR10J1, and BPIFA2. Each is linked with RBBP8 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBBP8-to-partner and partner-to-RBBP8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OOSP2 grouped by RBBP8-low versus RBBP8-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBBP8→partner) and Y-score (partner→RBBP8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	OOSP2 →	+0.017	+4.781	<.001	.003	3	1
BREAST	OR10J1 →	+0.425	+4.781	<.001	.003	3	1
CNS	BPIFA2 →	+0.267	+4.315	<.001	.006	3	1
CNS	VN1R4 →	+0.073	+4.754	<.001	.005	3	1
LUNG_NSCLC_LUAD	FABP9 →	+0.042	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	PRAMEF11 →	+0.006	+5.662	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

OOSP2 by RBBP8 expression — BREAST

Explore this box plot interactively →