RBBP7

Across TCGA pan-cancer cohorts, RBBP7 mass-spec protein is linked to patient survival in 8 of 34 cancer types, making it a survival-associated RBBP7 data layer compared with 24 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher RBBP7 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated RBBP7 expression acts as an unfavorable survival marker, although some lineages such as LSCC and LUAD show a favorable association.

HNSC, LSCC, and LUAD are the cancer types where RBBP7 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	All	0.231	0.818	.001	74	view →
LSCC	OS	Quartile	All	1.000	0.758	.011	29	view →
LUAD	OS	Quartile	II,III,IV	1.000	0.738	.006	28	view →
PDAC	DFS	Quartile	All	0.899	0.611	.001	23	view →
OV	DFS	Median	All	0.854	1.000	.025	8	view →
COAD	DFS	Median	IV	0.493	0.944	.031	6	view →
CCRCC	DFS	Quartile	All	0.314	0.873	.010	6	view →
GBM	DFS	Quartile	All	0.686	0.904	.031	1	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

RBBP7–HNSC (DFS)

Open the HNSC breakdown →