RBBP7

Across TCGA patient cohorts, RBBP7 mutation is significantly associated with the RNA expression of many other genes, with 2,559 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBBP7-associated genes across cancer lineages are MIR572, RN7SL847P, and KIAA0930. Each is linked with RBBP7 in more than 2 cancer types. Because this analysis shows association rather than direction, both RBBP7-to-partner and partner-to-RBBP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR572 grouped by RBBP7-low versus RBBP7-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBBP7→partner) and Y-score (partner→RBBP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	MIR572 →	+0.527	+5.474	<.001	.005	3	3
CESC	RN7SL847P →	+0.260	+5.010	<.001	.009	3	2
UCEC	KIAA0930 →	+0.458	+1.879	<.001	<.001	3	2
UCEC	GABRE →	-0.660	-2.115	.001	<.001	3	2
UCEC	BAG1 →	+0.595	+2.115	<.001	<.001	3	2
UCEC	ZNF330 →	+0.323	+1.857	.006	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,559 associations by consensus.

MIR572 by RBBP7 expression — LUSC

Explore this box plot interactively →