RBBP7

Across TCGA cell cohorts, RBBP7 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,856 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RBBP7-associated GO terms across cancer lineages are DNA strand elongation, Lagging strand elongation, and Regulation of metaphase/anaphase transition of cell cycle. Each is linked with RBBP7 in more than 15 cancer types. Because this analysis shows association rather than direction, both RBBP7-to-partner and partner-to-RBBP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA strand elongation grouped by RBBP7-low versus RBBP7-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RBBP7→partner) and Y-score (partner→RBBP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	DNA strand elongation →	+0.147	+1.029	<.001	<.001	3	16
LUNG_NSCLC_LUSC	Lagging strand elongation →	+0.156	+1.128	.009	.002	3	16
UPPER_AERODIGESTIVE_TRACT	Regulation of metaphase/anaphase transition of cell cycle →	+0.103	+0.913	.006	.007	3	15
UPPER_AERODIGESTIVE_TRACT	Regulation of mitotic metaphase/anaphase transition →	+0.107	+0.964	.006	.004	3	15
PANCREAS	DNA replication initiation →	+0.155	+0.778	.001	.001	3	15
OVARY	Regulation of cell cycle checkpoint →	+0.106	+0.847	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,856 associations by consensus.

DNA strand elongation by RBBP7 expression — BLOOD_Myeloma

Explore this box plot interactively →