RBBP7

Across TCGA cell cohorts, RBBP7 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RBBP7-associated genes across cancer lineages are CFHR2, TRIM49B, and DAOA. Each is linked with RBBP7 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBBP7-to-partner and partner-to-RBBP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CFHR2 grouped by RBBP7-low versus RBBP7-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBBP7→partner) and Y-score (partner→RBBP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CFHR2 →	+0.296	+4.539	<.001	.007	3	2
BLOOD_Leukemia	TRIM49B →	+0.140	+4.874	<.001	.002	3	1
BLOOD_Leukemia	DAOA →	+0.036	+4.539	<.001	.007	3	1
LARGE_INTESTINE	B3GALT1 →	+0.391	+3.426	<.001	.007	3	1
LARGE_INTESTINE	OR4F21 →	+0.163	+4.141	<.001	<.001	3	1
LARGE_INTESTINE	YIPF7 →	+0.091	+4.141	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

CFHR2 by RBBP7 expression — BLOOD_Leukemia

Explore this box plot interactively →