RBBP6

Across TCGA patient cohorts, RBBP6 protein abundance is significantly associated with the RNA expression of many other genes, with 17,114 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RBBP6-associated genes across cancer lineages are HPGDS, NEK2, and F13A1. Each is linked with RBBP6 in more than 7 cancer types. Because this analysis shows association rather than direction, both RBBP6-to-partner and partner-to-RBBP6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RBBP6 versus HPGDS in GBM, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBBP6→partner) and Y-score (partner→RBBP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	HPGDS →	-0.816	-0.215	<.001	.001	3	8
LUAD	NEK2 →	+1.194	+0.198	<.001	<.001	3	8
COAD	F13A1 →	-1.545	-0.188	<.001	<.001	3	7
BRCA	MTBP →	+0.668	+0.232	.001	<.001	3	7
BRCA	NAV3 →	-1.016	-0.276	.001	<.001	3	7
OV	SNRPE →	+0.821	+0.472	.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,114 associations by consensus.

RBBP6 vs HPGDS — GBM

Explore this scatter interactively →