RBBP6

Across TCGA patient cohorts, RBBP6 mutation is significantly associated with the RNA expression of many other genes, with 6,116 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBBP6-associated genes across cancer lineages are RNA5SP411, GNPNAT1, and EARS2. Each is linked with RBBP6 in more than 3 cancer types. Because this analysis shows association rather than direction, both RBBP6-to-partner and partner-to-RBBP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP411 grouped by RBBP6-low versus RBBP6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBBP6→partner) and Y-score (partner→RBBP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP411 →	+0.614	+1.352	<.001	.002	3	4
UCEC	GNPNAT1 →	+0.522	+1.958	<.001	<.001	3	3
UCEC	EARS2 →	+0.432	+1.440	<.001	<.001	3	3
UCEC	NEIL3 →	+0.518	+2.606	<.001	<.001	3	3
UCEC	ABHD5 →	+0.631	+2.091	<.001	<.001	3	3
UCEC	RRP9 →	+0.311	+2.123	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,116 associations by consensus.

RNA5SP411 by RBBP6 expression — UCEC

Explore this box plot interactively →