RBBP6

Across TCGA cell cohorts, RBBP6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,903 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RBBP6-associated GO terms across cancer lineages are Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway, Late viral transcription, and mRNA 3'-end processing. Each is linked with RBBP6 in more than 16 cancer types. Because this analysis shows association rather than direction, both RBBP6-to-partner and partner-to-RBBP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway grouped by RBBP6-low versus RBBP6-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RBBP6→partner) and Y-score (partner→RBBP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway →	+0.140	+0.767	<.001	<.001	3	17
LUNG_SCLC	Late viral transcription →	+0.133	+0.463	<.001	<.001	3	16
BLOOD_Lymphoma	mRNA 3'-end processing →	+0.087	+0.854	<.001	<.001	3	16
BLOOD_Lymphoma	Regulation of mRNA processing →	+0.080	+0.722	<.001	<.001	3	16
SOFT_TISSUE	Termination of RNA polymerase II transcription →	+0.132	+0.640	<.001	<.001	3	16
LUNG_SCLC	Nuclear-transcribed mRNA catabolic process →	+0.060	+0.548	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,903 associations by consensus.

Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway by RBBP6 expression — BONE

Explore this box plot interactively →