RBAK

Across TCGA pan-cancer cohorts, RBAK mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated RBAK data layer compared with 22 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher RBAK mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated RBAK expression acts as an unfavorable survival marker.

LSCC and GBM are the cancer types where RBAK mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Quartile	All	0.812	0.960	.020	8	view →
GBM	DFS	Tertile	All	0.279	0.597	.027	4	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

RBAK–LSCC (OS)

Open the LSCC breakdown →