RBAK

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RBAK protein abundance is significantly associated with the RNA expression of many other genes, with 8,301 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RBAK-associated genes across cancer lineages are PRMT1, TRIM28, and CCDC150. Each is linked with RBAK in more than 2 cancer types. Because this analysis shows association rather than direction, both RBAK-to-partner and partner-to-RBAK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RBAK versus PRMT1 in HNSC, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBAK→partner) and Y-score (partner→RBAK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCPRMT1 →+1.095+0.815.004.00233
HNSCTRIM28 →+1.065+0.750.009.00333
HNSCCCDC150 →+1.012+0.621<.001.00733
HNSCPHB →+0.827+0.992<.001.00133
HNSCPOLE →+1.014+0.703.001.00133
HNSCCDCA2 →+1.649+0.869<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 8,301 associations by consensus.

RBAK vs PRMT1 — HNSC

Per-sample scatter of RBAK vs PRMT1 in HNSC (Pearson r = 0.53).

Explore this scatter interactively →

Exploration