RBAK

Across TCGA patient cohorts, RBAK mutation is significantly associated with the RNA expression of many other genes, with 3,211 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBAK-associated genes across cancer lineages are LINC00474, MIR378E, and RN7SL7P. Each is linked with RBAK in more than 2 cancer types. Because this analysis shows association rather than direction, both RBAK-to-partner and partner-to-RBAK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC00474 grouped by RBAK-low versus RBAK-high in LGG.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBAK→partner) and Y-score (partner→RBAK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	LINC00474 →	+0.048	+5.602	.005	.004	3	3
BRCA	MIR378E →	+0.745	+4.298	<.001	.009	3	3
LUAD	RN7SL7P →	+0.342	+3.584	<.001	.002	3	3
LUAD	SLC30A6P1 →	+0.737	+3.123	<.001	.007	3	3
UCEC	PARP2 →	+0.469	+4.000	<.001	<.001	3	3
UCEC	IMMP1L →	+0.310	+1.662	.008	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,211 associations by consensus.

LINC00474 by RBAK expression — LGG

Explore this box plot interactively →