RB1CC1

Across TCGA pan-cancer cohorts, RB1CC1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated RB1CC1 data layer compared with 25 for mass-spec protein and 11 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher RB1CC1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated RB1CC1 expression acts as an unfavorable survival marker, although some lineages such as GBM and LUAD show a favorable association.

PDAC, GBM, and LUAD are the cancer types where RB1CC1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Tertile	II,III,IV	0.386	0.607	.002	36	view →
GBM	DFS	Tertile	All	0.943	0.609	.001	13	view →
LUAD	DFS	Median	II,III,IV	0.713	0.344	.020	9	view →
LSCC	DFS	Median	All	0.505	0.943	<.001	7	view →
CCRCC	OS	Tertile	II,III,IV	0.959	0.277	.024	6	view →
HNSC	OS	Tertile	IV	0.872	0.631	.039	4	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

RB1CC1–PDAC (OS)

Open the PDAC breakdown →