RB1CC1

Across TCGA patient cohorts, RB1CC1 mutation is significantly associated with the RNA expression of many other genes, with 4,354 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RB1CC1-associated genes across cancer lineages are GFM2, PINLYP, and LINC01072. Each is linked with RB1CC1 in more than 3 cancer types. Because this analysis shows association rather than direction, both RB1CC1-to-partner and partner-to-RB1CC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GFM2 grouped by RB1CC1-low versus RB1CC1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RB1CC1→partner) and Y-score (partner→RB1CC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GFM2 →	+0.487	+1.661	<.001	<.001	3	4
CESC	PINLYP →	-1.129	-3.449	.001	.005	3	3
LIHC	LINC01072 →	+0.120	+5.305	<.001	<.001	3	3
LUAD	COMMD4P2 →	+0.091	+3.071	<.001	<.001	3	3
KIRP	DPRXP7 →	+0.130	+5.016	<.001	.002	3	3
UCEC	FCER1A →	-0.695	-1.788	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,354 associations by consensus.

GFM2 by RB1CC1 expression — UCEC

Explore this box plot interactively →