RAX2

Across TCGA patient cohorts, RAX2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,755 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RAX2-associated GO terms across cancer lineages are Microtubule polymerization, Negative regulation of mRNA processing, and Intracellular protein transmembrane transport. Each is linked with RAX2 in more than 10 cancer types. Because this analysis shows association rather than direction, both RAX2-to-partner and partner-to-RAX2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule polymerization grouped by RAX2-low versus RAX2-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAX2→partner) and Y-score (partner→RAX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Microtubule polymerization →	+0.071	+0.053	.002	<.001	2	11
STAD	Negative regulation of mRNA processing →	+0.047	+0.039	<.001	<.001	3	10
STAD	Intracellular protein transmembrane transport →	+0.045	+0.039	<.001	<.001	3	10
STAD	Methylation →	+0.041	+0.040	<.001	<.001	3	10
STAD	Regulation of chromatin organization →	+0.053	+0.039	<.001	<.001	3	10
STAD	Establishment of protein localization to mitochondrial membrane →	+0.051	+0.037	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,755 associations by consensus.

Microtubule polymerization by RAX2 expression — SCLC

Explore this box plot interactively →