RASSF8

Across TCGA patient cohorts, RASSF8 mutation is significantly associated with the RNA expression of many other genes, with 2,537 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RASSF8-associated genes across cancer lineages are RN7SL248P, MED28P4, and MIR4774. Each is linked with RASSF8 in more than 2 cancer types. Because this analysis shows association rather than direction, both RASSF8-to-partner and partner-to-RASSF8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by RASSF8-low versus RASSF8-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RASSF8→partner) and Y-score (partner→RASSF8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL248P →	+0.063	+3.307	<.001	.003	3	3
READ	MED28P4 →	+0.394	+5.039	<.001	.008	3	2
READ	MIR4774 →	+0.841	+6.257	<.001	.001	3	2
CESC	MIR549A →	+0.507	+6.342	<.001	.001	3	2
UCEC	KRTAP20-3 →	+0.061	+3.973	<.001	.006	3	2
UCEC	LINC02522 →	+0.627	+2.445	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,537 associations by consensus.

RN7SL248P by RASSF8 expression — UCEC

Explore this box plot interactively →