RASSF8

Across TCGA cell cohorts, RASSF8 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RASSF8-associated genes across cancer lineages are AVPR1B and OR1L1. Each is linked with RASSF8 in more than 1 cancer types. Because this analysis shows association rather than direction, both RASSF8-to-partner and partner-to-RASSF8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AVPR1B grouped by RASSF8-low versus RASSF8-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RASSF8→partner) and Y-score (partner→RASSF8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	AVPR1B →	+0.013	+5.415	<.001	.004	3	1
LARGE_INTESTINE	OR1L1 →	+0.039	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

AVPR1B by RASSF8 expression — SKIN

Explore this box plot interactively →