RASSF5

Across TCGA cell cohorts, RASSF5 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,753 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RASSF5-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Negative regulation of myoblast fusion, and Rho protein signal transduction. Each is linked with RASSF5 in more than 12 cancer types. Because this analysis shows association rather than direction, both RASSF5-to-partner and partner-to-RASSF5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by RASSF5-low versus RASSF5-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RASSF5→partner) and Y-score (partner→RASSF5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.109	+1.080	.001	.005	3	13
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.119	+1.189	<.001	.002	3	13
OESOPHAGUS	Rho protein signal transduction →	+0.117	+1.088	<.001	.005	3	12
URINARY_TRACT	CD8-positive, alpha-beta T cell differentiation →	+0.124	+1.557	.002	.002	3	11
URINARY_TRACT	CD8-positive, alpha-beta T cell activation →	+0.153	+1.536	.001	.008	3	11
URINARY_TRACT	Protein stabilization →	+0.071	+2.087	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,753 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by RASSF5 expression — OESOPHAGUS

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