RASSF4

Across TCGA cell cohorts, RASSF4 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,378 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RASSF4-associated GO terms across cancer lineages are Vesicle-mediated transport to the plasma membrane, Protein targeting to vacuole involved in autophagy, and Substrate adhesion-dependent cell spreading. Each is linked with RASSF4 in more than 11 cancer types. Because this analysis shows association rather than direction, both RASSF4-to-partner and partner-to-RASSF4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle-mediated transport to the plasma membrane grouped by RASSF4-low versus RASSF4-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RASSF4→partner) and Y-score (partner→RASSF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Vesicle-mediated transport to the plasma membrane →	+0.070	+1.313	.001	.001	3	12
BONE	Protein targeting to vacuole involved in autophagy →	+0.202	+1.391	.002	.006	3	11
CNS	Substrate adhesion-dependent cell spreading →	+0.122	+1.328	.001	<.001	3	11
URINARY_TRACT	Ribonucleoside diphosphate catabolic process →	+0.102	+1.245	.001	.002	3	11
BONE	Regulation of endocytosis →	+0.049	+1.209	.006	.002	2	12
BONE	Regulation of intracellular transport →	+0.059	+1.428	.007	.004	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,378 associations by consensus.

Vesicle-mediated transport to the plasma membrane by RASSF4 expression — BONE

Explore this box plot interactively →