RASSF3

Across TCGA patient cohorts, RASSF3 mutation is significantly associated with the RNA expression of many other genes, with 117 significant associations in total. COAD shows the largest number of these associations.

The most reproducible RASSF3-associated genes across cancer lineages are RN7SKP37, C18orf12, and OR52P2P. Each is linked with RASSF3 in more than 1 cancer types. Because this analysis shows association rather than direction, both RASSF3-to-partner and partner-to-RASSF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP37 grouped by RASSF3-low versus RASSF3-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RASSF3→partner) and Y-score (partner→RASSF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RN7SKP37 →	+0.544	+6.003	<.001	.002	3	2
UCEC	C18orf12 →	+0.237	+4.298	.001	<.001	3	2
COAD	OR52P2P →	+0.407	+5.602	<.001	.004	3	2
COAD	OR10P1 →	+0.279	+5.516	<.001	.004	3	2
UCEC	PLCL2-AS1 →	+0.344	+2.914	<.001	.008	3	2
COAD	RN7SKP79 →	+0.974	+5.080	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 117 associations by consensus.

RN7SKP37 by RASSF3 expression — COAD

Explore this box plot interactively →