RASSF1

Across TCGA patient cohorts, RASSF1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,474 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RASSF1-associated genes across cancer lineages are CD4, ATPSCKMT, and RMND5A. Each is linked with RASSF1 in more than 3 cancer types. Because this analysis shows association rather than direction, both RASSF1-to-partner and partner-to-RASSF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RASSF1 versus CD4 in GBM, with a Pearson correlation of 0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RASSF1→partner) and Y-score (partner→RASSF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CD4 →	+0.729	+0.302	.002	.007	3	4
LSCC	ATPSCKMT →	-0.553	-0.274	<.001	<.001	3	4
LSCC	RMND5A →	-0.562	-0.242	<.001	<.001	3	4
LSCC	ATMIN →	-0.408	-0.251	.001	.003	3	4
GBM	ZBTB39 →	-0.440	-0.407	<.001	<.001	3	4
GBM	MLKL →	+0.558	+0.282	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,474 associations by consensus.

RASSF1 vs CD4 — GBM

Explore this scatter interactively →