RASSF1

Across TCGA cell cohorts, RASSF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,681 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RASSF1-associated GO terms across cancer lineages are Regulation of focal adhesion assembly, Regulation of cell-substrate junction assembly, and Positive regulation of focal adhesion assembly. Each is linked with RASSF1 in more than 12 cancer types. Because this analysis shows association rather than direction, both RASSF1-to-partner and partner-to-RASSF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of focal adhesion assembly grouped by RASSF1-low versus RASSF1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RASSF1→partner) and Y-score (partner→RASSF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of focal adhesion assembly →	+0.132	+0.922	<.001	<.001	3	13
BONE	Regulation of cell-substrate junction assembly →	+0.132	+0.922	<.001	<.001	3	13
BONE	Positive regulation of focal adhesion assembly →	+0.177	+0.876	<.001	<.001	3	13
BREAST	Regulation of hippo signaling →	+0.080	+1.061	<.001	<.001	3	13
BONE	Regulation of cell-substrate junction organization →	+0.180	+1.153	<.001	<.001	3	12
BONE	Regulation of protein K48-linked ubiquitination →	+0.175	+1.294	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,681 associations by consensus.

Regulation of focal adhesion assembly by RASSF1 expression — BONE

Explore this box plot interactively →