RASSF1

Across TCGA cell cohorts, RASSF1 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. CNS shows the largest number of these associations.

The most reproducible RASSF1-associated genes across cancer lineages are HELT. Each is linked with RASSF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RASSF1-to-partner and partner-to-RASSF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HELT grouped by RASSF1-low versus RASSF1-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RASSF1→partner) and Y-score (partner→RASSF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	HELT →	+0.055	+5.321	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

HELT by RASSF1 expression — CNS

Explore this box plot interactively →