RASGRP2

Across TCGA cell cohorts, RASGRP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,821 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RASGRP2-associated GO terms across cancer lineages are Positive regulation of DNA repair, Positive regulation of DNA metabolic process, and Protein-DNA complex organization. Each is linked with RASGRP2 in more than 10 cancer types. Because this analysis shows association rather than direction, both RASGRP2-to-partner and partner-to-RASGRP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA repair grouped by RASGRP2-low versus RASGRP2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RASGRP2→partner) and Y-score (partner→RASGRP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of DNA repair →	+0.058	+1.820	.008	.001	3	11
BONE	Positive regulation of DNA metabolic process →	+0.052	+1.367	.008	.003	3	11
BONE	Protein-DNA complex organization →	+0.062	+1.435	.001	.001	3	11
LUNG_NSCLC_LUAD	Potassium ion import across plasma membrane →	-0.225	-0.807	<.001	<.001	3	10
BREAST	Regulation of DNA repair →	+0.046	+0.521	.008	.009	2	11
OESOPHAGUS	Nucleotide biosynthetic process →	+0.075	+1.095	.005	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,821 associations by consensus.

Positive regulation of DNA repair by RASGRP2 expression — BONE

Explore this box plot interactively →